MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid peptide encoded within the mitochondrial genome. Research has examined its role as a mitochondria-derived signaling molecule with effects on AMPK activation, glucose metabolism, and insulin sensitivity pathways in various research models.
Studies have investigated its nuclear translocation under metabolic stress conditions and its influence on gene expression related to cellular homeostasis. As a mitochondria-derived peptide, it represents a novel class of research compounds at the intersection of mitochondrial biology and metabolic research.
Each vial is supplied as lyophilized powder, third-party tested via LC-MS analysis, and ships with a Certificate of Analysis.
Specifications: CAS: 1627580-64-6 | MW: 2,174.6 Da | Purity: >99% | Form: Lyophilized Powder | Storage: -20°C long-term / 4°C short-term
⚠️ For Research Use Only. Not intended for human consumption, medical, diagnostic, or therapeutic purposes.




